Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 8/20 | 0.60 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.60 |
| ▸ | USP10 | Q14694 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716037 | 0.79 | USP7 (0.37) | USP7USP47USP10TDP1KDM4E | |
| SCHEMBL3717157 | 0.79 | USP7 (0.69) | USP7USP47TDP1PDE7AMAPT | |
| SCHEMBL3716798 | 0.77 | USP7 (0.59) | USP7USP47TDP1PDE7AKDM4E | |
| SCHEMBL3715105 | 0.77 | USP7 (0.45) | USP7USP47USP10TDP1PDE7A | |
| SCHEMBL28903536 | 0.76 | USP7 (0.60) | USP7USP47USP10TDP1ATM | |
| SCHEMBL2680882 | 0.76 | USP7 (0.80) | USP7USP47USP10TDP1ATM | |
| SCHEMBL3714971 | 0.75 | USP7 (0.48) | USP7USP47USP10TDP1PDE7A | |
| SCHEMBL3715754 | 0.75 | USP7 (0.72) | USP7USP47TDP1PDE7AKDM4E | |
| SCHEMBL3720903 | 0.75 | USP7 (0.43) | USP7USP47TDP1PDE7AKDM4E | |
| SCHEMBL29493045 | 0.75 | USP7 (1.00) | USP7USP47USP10TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |