Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 14/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CLPP | Q16740 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723937 | 0.91 | PRLHR (0.42) | PRLHREGLN1HTR2CHTR2BGPR18 | |
| SCHEMBL3716376 | 0.84 | PRLHR (0.44) | PRLHR | |
| SCHEMBL434541 | 0.82 | PRLHR (0.64) | PRLHR | |
| SCHEMBL3714704 | 0.80 | HTR2C (0.40) | PRLHREGLN1HTR2CHTR2BPDE2A | |
| SCHEMBL3713567 | 0.80 | PRLHR (0.49) | PRLHRHTR2CHTR2B | |
| SCHEMBL3720701 | 0.79 | PRLHR (0.42) | PRLHREGLN1HTR2CHTR2BPDE2A | |
| SCHEMBL3714330 | 0.78 | PRLHR (0.55) | PRLHR | |
| SCHEMBL3716287 | 0.78 | PRLHR (0.65) | PRLHR | |
| SCHEMBL3713280 | 0.77 | PRLHR (0.64) | PRLHR | |
| SCHEMBL3719992 | 0.77 | PRLHR (0.43) | PRLHREGLN1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |