SCHEMBL371666

SCHEMBL371666

CCCCCCCCCCCCc1cc(Br)sc1-c1nc2sc(-c3sc(Br)cc3CCCCCCCCCCCC)nc2s1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.33
PTGS2 P35354 3/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
TYR P14679 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KCNH2 Q12809 1/20 0.33
TLR8 Q9NR97 3/20 0.33
GPR35 Q9HC97 1/20 0.32
HTR2A P28223 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
USP2 O75604 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14122782 1.00 ALOX5 (0.33) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL15940364 1.00 ALOX5 (0.33) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL10301450 1.00 ALOX5 (0.33) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL163731 1.00 ALOX5 (0.33) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL15947141 0.93 ALOX5 (0.30) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL16866425 0.93 ALOX5 (0.30) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL15947136 0.93 ALOX5 (0.30) ALOX5PTGS2CYP3A4MAPTMEN1
SCHEMBL17676335 0.89 HTR2A (0.32) HTR2A
SCHEMBL12921571 0.89 MEN1 (0.32) ALOX5CYP3A4MAPTMEN1TP53
SCHEMBL12921574 0.89 MEN1 (0.32) ALOX5CYP3A4MAPTMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247803-B2 Organic transistor including an organic semicnductor layer and method for fabricating the same LG CHEM, LTD. (KR) 2012-08-21 US disclosed
EP-2410002-A1 COMPOUND AND ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2012-01-25 EP disclosed
EP-2410017-A1 COMPOSITION AND ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2012-01-25 EP disclosed
US-20110309350-A1 COMPOUND AND DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-22 US disclosed
US-20110309350-A1 COMPOUND AND DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-22 US disclosed
US-20110303293-A1 COMPOSITION AND DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-15 US disclosed
US-20110303293-A1 COMPOSITION AND DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-15 US disclosed
US-20100084637-A1 ORGANIC TRANSISTOR AND METHOD FOR FABRICATING THE SAME LG CHEM, LTD. (KR) 2010-04-08 US disclosed