Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075826 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CDC25BMAPTKDM4EL3MBTL1 | |
| SCHEMBL5994480 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1KDM4EL3MBTL1 | |
| SCHEMBL8993717 | 0.82 | ALDH1A1 (0.53) | PKMALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL341388 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL5996915 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL13363938 | 0.76 | KDM4E (0.52) | ALDH1A1KDM4EL3MBTL1HPGDTP53 | |
| SCHEMBL5997134 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL13363927 | 0.72 | TSHR (0.52) | PKMALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL30898834 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL17490913 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132547-A2 | OXAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132547-A2 | OXAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |