⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28060817 | 0.98 | BLM (0.39) | — | |
| SCHEMBL7386649 | 0.93 | TSHR (0.36) | — | |
| SCHEMBL25333031 | 0.80 | — | — | |
| SCHEMBL2130103 | 0.80 | — | — | |
| SCHEMBL7809859 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL17912325 | 0.75 | — | — | |
| SCHEMBL4572652 | 0.75 | CHRNB2 (0.36) | — | |
| SCHEMBL4572654 | 0.72 | HSD17B3 (0.35) | — | |
| SCHEMBL22801155 | 0.72 | — | — | |
| SCHEMBL4572643 | 0.71 | FFAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107532185-A | Process for producing hydroxy-L-pipecolic acid | 株式会社API | 2018-01-02 | — | — | CN | claimed |
| CN-102070526-A | Method for synthesizing 3-aza-bicyclo[4.1.0]heptane-6-formic acid with protective group | WUXI APP INC | 2011-05-25 | — | — | CN | claimed |
| EP-0078191-B1 | COLLAGEN INHIBITING COMPOSITIONS AND PROCESSES FOR MANUFACTURING AND USING THE SAME | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1986-09-03 | — | — | EP | claimed |
| US-4428939-A | POLYMERIC HYDROXYPROLINE FOR REDUCTION OF SCAR TISSUE | COLLEGE OF MEDICINE AND DENTISTRY OF NEW JERSEY | 1984-01-31 | — | — | US | claimed |
| EP-0078191-A2 | Collagen inhibiting compositions and processes for manufacturing and using the same | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1983-05-04 | — | — | EP | claimed |
| WO-2024022487-A1 | AMINOHETEROARYL KINASE INHIBITORS | Allorion Therapeutics Inc (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023186060-A1 | KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023184327-A1 | KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20220133671-A1 | ANTI-FIBROTIC NEU3 INHIBITOR COMPOUNDS AND METHODS OF USE | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2022-05-05 | — | — | US | disclosed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022053010-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-17 | — | — | WO | disclosed |
| US-4221912-A | Dithio derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221912-A | Dithio derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4217458-A | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4217458-A | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4217458-A | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4198515-A | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198515-A | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198515-A | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |