Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19938054 | 0.84 | HPGD (0.69) | MEN1KMT2AHPGDRAB9ALMNA | |
| SCHEMBL19941261 | 0.81 | MEN1 (0.57) | MEN1KMT2AHPGDRAB9ALMNA | |
| SCHEMBL9969774 | 0.81 | MEN1 (0.57) | MEN1KMT2AHPGDRAB9ALMNA | |
| SCHEMBL11744132 | 0.81 | MAPK1 (0.66) | MEN1KMT2AHPGDRAB9ALMNA | |
| SCHEMBL9969391 | 0.81 | MEN1 (0.53) | MEN1KMT2AHPGDRAB9ALMNA | |
| SCHEMBL28137985 | 0.79 | RPS6KB1 (0.46) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2092275 | 0.78 | MEN1 (0.60) | MEN1KMT2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5209200 | 0.77 | LMNA (0.58) | MEN1KMT2ARAB9ALMNAHTT | |
| SCHEMBL2091913 | 0.77 | MEN1 (0.62) | MEN1KMT2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14270128 | 0.76 | MEN1 (0.50) | MEN1KMT2AHPGDRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |