Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 5/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723437 | 0.89 | CYP3A4 (0.38) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3719961 | 0.87 | USP7 (0.40) | USP7USP47MAPTLMNAFBP1 | |
| SCHEMBL3719652 | 0.83 | USP7 (0.60) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3723562 | 0.79 | USP47 (0.43) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3715105 | 0.79 | USP7 (0.45) | USP7USP47MAPTLMNAHTT | |
| SCHEMBL3720903 | 0.77 | USP7 (0.43) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3717084 | 0.77 | USP7 (0.46) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3714784 | 0.77 | USP47 (0.48) | USP7USP47MAPTPADI4HTT | |
| SCHEMBL2682523 | 0.76 | USP47 (0.70) | USP7USP47MAPTLMNAPADI4 | |
| SCHEMBL3719648 | 0.76 | USP7 (0.43) | USP7USP47MAPTLMNAPADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |