⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL28158524 | 0.67 | — | — | |
| SCHEMBL144861 | 0.63 | — | — | |
| SCHEMBL27655258 | 0.62 | HDAC8 (0.33) | — | |
| SCHEMBL623156 | 0.62 | CA2 (0.39) | — | |
| SCHEMBL3712112 | 0.61 | — | — | |
| SCHEMBL3789219 | 0.61 | — | — | |
| SCHEMBL1644245 | 0.61 | — | — | |
| SCHEMBL1510604 | 0.61 | — | — | |
| SCHEMBL9231132 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735903-A1 | Negative working lithographic printing plate precursors comprising a hyperbranched binder material | Eastman Kodak Company (US) | 2014-05-28 | — | — | EP | disclosed |
| US-8658650-B2 | Substituted 1,1,3,1-tetraoxidobenzo[D][1,3,2]dithiazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | VANDERBILT UNIVERSITY | 2014-02-25 | — | — | US | disclosed |
| US-20110319429-A1 | SUBSTITUTED 1,1,3,1-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY | 2011-12-29 | — | — | US | disclosed |
| EP-2393785-A1 | SUBSTITUTED 1,1,3,3-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | Vanderbilt University (US) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010088406-A1 | SUBSTITUTED 1,1,3,3-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY (US) | 2010-08-05 | — | — | WO | disclosed |
| US-7560221-B2 | Lithographic printing plate precursors with mercapto-functionalized free-radical polymerizable monomers | KODAK GRAPHIC COMMUNICATIONS GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-20070148583-A1 | Lithographic printing plate precursors with mercapto-functionlalized free-radical polymerizable monomers | KODAK POLYCHROME GRAPHICS, GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| EP-1706790-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSORS WITH MERCAPTO-FUNCTIONALIZED FREE-RADICAL POLYMERIZABLE MONOMERS | Kodak Polychrome Graphics GmbH (DE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005071488-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSORS WITH MERCAPTO-FUNCTIONALIZED FREE-RADICAL POLYMERIZABLE MONOMERS | KODAK POLYCHROME GRAPHICS GMBH (DE) | 2005-08-04 | — | — | WO | disclosed |