Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 5/20 | 0.46 |
| ▸ | ACACA | Q13085 | 5/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CDC42 | P60953 | 1/20 | 0.41 |
| ▸ | RAC1 | P63000 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635084 | 0.80 | KMT2A (0.52) | UGT2B7ACACBACACACYP1A2CYP2C19 | |
| SCHEMBL3717912 | 0.79 | ACACB (0.49) | ACACBACACATDP1L3MBTL1PTGS2 | |
| SCHEMBL3720525 | 0.78 | ACACB (0.48) | ACACBACACATDP1L3MBTL1PTGS2 | |
| SCHEMBL3717475 | 0.78 | ACACB (0.73) | ACACBACACA | |
| SCHEMBL3808755 | 0.78 | ACACB (0.73) | ACACBACACA | |
| SCHEMBL5610446 | 0.78 | UGT2B7 (0.82) | UGT2B7ABCB11PTGS2AKR1C3AKR1C2 | |
| SCHEMBL3727560 | 0.77 | ACACB (0.58) | ACACBACACATDP1L3MBTL1CYP2C9 | |
| SCHEMBL23255697 | 0.77 | ABCB11 (0.66) | UGT2B7ABCB11TDP1L3MBTL1PTGS2 | |
| SCHEMBL2423910 | 0.77 | ABCB11 (0.66) | UGT2B7ABCB11TDP1L3MBTL1PTGS2 | |
| SCHEMBL9120097 | 0.77 | ABCB11 (0.66) | UGT2B7ABCB11TDP1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |