Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pentaerythritol Tetranitrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentaerythritol Tetranitrate SCHEMBL920358 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1 | |
| Pentaerythritol Tetranitrate SCHEMBL5940085 | 0.97 | ALDH1A1 (0.94) | ALDH1A1 | |
| SCHEMBL7888554 | 0.92 | ALDH1A1 (0.84) | ALDH1A1 | |
| Pentaerythritol Tetranitrate SCHEMBL1028496 | 0.92 | ALDH1A1 (0.84) | ALDH1A1 | |
| Pentaerythritol Tetranitrate SCHEMBL15543872 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TSHR | |
| SCHEMBL7891079 | 0.87 | ALDH1A1 (0.76) | ALDH1A1 | |
| Pentaerythritol Tetranitrate SCHEMBL6686407 | 0.85 | ALDH1A1 (0.73) | ALDH1A1TSHR | |
| Pentrinitrol SCHEMBL122322 | 0.84 | ALDH1A1 (0.71) | ALDH1A1TDP1 | |
| SCHEMBL7894787 | 0.84 | ALDH1A1 (0.71) | ALDH1A1 | |
| SCHEMBL8277378 | 0.84 | ALDH1A1 (0.71) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 25613 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637396-B1 | Explosives using thermally expandable microspheres in a solid matrix | TRIAD NATIONAL SECURITY, LLC (US) | 2026-05-26 | — | — | US | claimed |
| CN-122036441-A | Core-shell structure composite energetic material and preparation method thereof | 大连理工大学 | 2026-05-15 | — | — | CN | claimed |
| US-20260133017-A1 | LINEAR SHAPED CHARGE WITH INTEGRATED SHOCK WAVE AMPLIFICATION ELEMENT | MAXAMCORP INT S L (ES) | 2026-05-14 | — | — | US | claimed |
| CN-122016816-A | Method for automatically analyzing deterioration degree of vegetables and fruits | 广东绿鑫源农产品有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122012804-A | SNP molecular marker related to capsicum fruit orientation, primer set and application thereof | 浙江大学海南研究院 | 2026-05-12 | — | — | CN | claimed |
| EP-3433086-B1 | ENERGETIC MATERIALS | TNO (NL) | 2026-05-06 | — | — | EP | claimed |
| EP-4127588-B1 | METHOD OF AND CHARGE FOR CLEANING INCINERATOR HEAT EXCHANGERS | CUSTOS TYCHE BEHEER B V (NL) | 2026-05-06 | — | — | EP | claimed |
| US-20260115188-A1 | METHODS OF TREATING CENTERAL NERVOUS SYSTEM DISORDERS COMPRISING ADMINISTERING DEUTERATED LUMATEPERONE AND A NITRIC OXIDE DONOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2026-04-30 | — | — | US | claimed |
| US-12605345-B2 | Transdermal drug delivery system | BioPhysics Pharma, Inc. (US) | 2026-04-21 | — | — | US | claimed |
| EP-3338813-B2 | MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER | BSN MEDICAL GMBH (DE) | 2026-04-15 | — | — | EP | claimed |
| US-4009060-A | Primer composition for use with explosive charges | ATLAS POWDER COMPANY (US) | 1977-02-22 | — | — | US | claimed |
| US-4000021-A | Process for suspending particulate additives in molten TNT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-12-28 | — | — | US | claimed |
| US-3985279-A | Method for explosive welding tubular members using a mandrel | ALCAN RESEARCH AND DEVELOPMENT LIMITED (CA) | 1976-10-12 | — | — | US | claimed |
| US-3967989-A | High energy propellant compositions including vinyl decaborane-polyester copolymer binder | ROHM AND HAAS COMPANY (US) | 1976-07-06 | — | — | US | claimed |
| US-3960560-A | SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | claimed |
| US-3958206-A | CHEMICALLY AUGMENTED ELECTRICAL FUSE | GENERAL ELECTRIC COMPANY (US) | 1976-05-18 | — | — | US | claimed |
| US-3955505-A | Detonating apparatus | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) | 1976-05-11 | — | — | US | claimed |
| US-3945322-A | Through-bulkhead explosion initiation | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-03-23 | — | — | US | claimed |
| US-3943017-A | SELF SUPPORTING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-03-09 | — | — | US | claimed |
| US-3939941-A | Fuse cord | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1976-02-24 | — | — | US | claimed |