Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 11/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719845 | 0.88 | GAA (0.40) | GHSRGAAHPGDCYP2C9CYP2C19 | |
| SCHEMBL3715353 | 0.88 | GAA (0.40) | GHSRGAAHPGDCYP2C9CYP2C19 | |
| SCHEMBL3714768 | 0.81 | MEN1 (0.40) | HSD11B1CA12CA1CA2CA7 | |
| SCHEMBL3713712 | 0.73 | LIMK2 (0.42) | HPGD | |
| SCHEMBL4970907 | 0.72 | DPP4 (0.31) | — | |
| SCHEMBL2903872 | 0.70 | — | — | |
| SCHEMBL2904347 | 0.70 | — | — | |
| SCHEMBL3901950 | 0.70 | GAA (0.51) | GHSRGAAHPGDHSD11B1 | |
| SCHEMBL20370207 | 0.69 | GAA (0.76) | GAAHPGDHSD11B1CA12CA1 | |
| SCHEMBL16254905 | 0.68 | GAA (0.84) | GAAHPGDHSD11B1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |