Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.37 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792480 | 0.91 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1465979 | 0.86 | PTGDR2 (0.46) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3718032 | 0.85 | PTGDR2 (0.44) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1467543 | 0.85 | PTGDR2 (0.47) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1465686 | 0.84 | ALDH1A1 (0.44) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3724416 | 0.84 | ALDH1A1 (0.42) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1466211 | 0.83 | PTGDR2 (0.47) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1465369 | 0.82 | ALDH1A1 (0.47) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1465051 | 0.82 | PTGDR2 (0.51) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3724053 | 0.81 | ALDH1A1 (0.45) | PTGDR2ALDH1A1LMNAMAPTHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |