Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.37 |
| ▸ | BRAF | P15056 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720672 | 0.89 | ACACB (0.38) | ACACBBRAFMMP9ACACAHCRTR1 | |
| SCHEMBL3724126 | 0.85 | ACACB (0.48) | ACACBMMP9ALOX5ACACA | |
| SCHEMBL3723775 | 0.85 | ACACB (0.46) | ACACBALOX5ACACA | |
| SCHEMBL3716931 | 0.84 | PDE4B (0.42) | — | |
| SCHEMBL3802819 | 0.83 | ACACB (0.37) | ACACBBRAFMMP9ALOX5ACACA | |
| SCHEMBL3722861 | 0.83 | — | — | |
| SCHEMBL3722995 | 0.83 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL3719940 | 0.82 | ACACA (0.48) | ACACBMMP9ACACAHCRTR1TDP1 | |
| SCHEMBL3720613 | 0.81 | ACACB (0.48) | ACACBALOX5ACACA | |
| SCHEMBL3720899 | 0.81 | ACACB (0.51) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |