Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547992 | 1.00 | MEN1 (0.35) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL31182065 | 0.81 | — | — | |
| SCHEMBL2721766 | 0.81 | — | — | |
| Bicarbonate SCHEMBL2854209 | 0.81 | LMNA (0.37) | KMT2ACYP1A2CYP3A4PARP1LMNA | |
| SCHEMBL31520205 | 0.79 | CYP1A2 (0.43) | MEN1KMT2ACYP1A2TDP1KDM4E | |
| SCHEMBL4084297 | 0.79 | CYP1A2 (0.43) | MEN1KMT2ACYP1A2TDP1KDM4E | |
| Bicarbonate SCHEMBL1296431 | 0.76 | CHEK1 (0.38) | MEN1KMT2ATDP1PARP1KDM4E | |
| SCHEMBL1783621 | 0.75 | — | — | |
| SCHEMBL5381799 | 0.75 | KDM4E (0.37) | KMT2ACYP1A2CYP3A4KDM4ELMNA | |
| Bicarbonate SCHEMBL10625713 | 0.75 | CHEK1 (0.38) | MEN1KMT2ATDP1PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715624-A1 | PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | claimed |
| EP-2398781-A1 | 1,4-BENZODIAZEPIN-2-ON DERIVATIVES | MSD K.K. (JP) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010095766-A1 | 1,4-BENZODIAZEPIN-2-ON DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-08-26 | — | — | WO | disclosed |
| EP-0715624-A1 | PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |