Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410285 | 0.85 | TP53 (0.37) | — | |
| SCHEMBL410987 | 0.82 | — | — | |
| SCHEMBL6066126 | 0.81 | — | — | |
| SCHEMBL30087015 | 0.80 | TP53 (0.32) | — | |
| SCHEMBL6066112 | 0.79 | TP53 (0.31) | — | |
| SCHEMBL6064946 | 0.78 | TP53 (0.33) | — | |
| Dibemethine SCHEMBL6065086 | 0.76 | TP53 (0.37) | — | |
| SCHEMBL6065799 | 0.75 | TAS1R3 (0.34) | — | |
| SCHEMBL6066084 | 0.75 | TP53 (0.33) | — | |
| SCHEMBL6064871 | 0.75 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142576-A1 | POLYETHYLENE, PROCESS AND CATALYST COMPOSITION FOR THE PREPARATION THEREOF | Basell Polyolefine GmbH (DE) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008132059-A1 | POLYETHYLENE, PROCESS AND CATALYST COMPOSITION FOR THE PREPARATION THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2008-11-06 | — | — | WO | disclosed |