SCHEMBL3718540

SCHEMBL3718540

Cc1ccc(Nc2ccc(-c3ccc(Nc4ccc(C)cc4)cc3-c3ccccc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.59
APP P05067 2/20 0.51
NPSR1 Q6W5P4 1/20 0.48
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 5/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 3/20 0.46
POLB P06746 1/20 0.46
GBA1 P04062 1/20 0.46
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6425012 0.95 HPGD (0.61) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL18389550 0.93 HPGD (0.60) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL18173610 0.93 HPGD (0.64) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL31245650 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL31707426 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL24279376 0.89 HPGD (0.68) HPGDNPSR1MEN1KMT2AMAPT
SCHEMBL29576303 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL19511796 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL20582564 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A
SCHEMBL29892249 0.89 ALDH1A1 (0.48) HPGDAPPNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010141323-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-12-09 WO disclosed