Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 19/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711767 | 1.00 | SLC6A9 (0.43) | SLC6A9SLC6A5LMNAHPGD | |
| SCHEMBL2125188 | 0.88 | SLC6A9 (0.39) | SLC6A9SLC6A5 | |
| SCHEMBL2126165 | 0.88 | SLC6A9 (0.39) | SLC6A9SLC6A5 | |
| SCHEMBL2126423 | 0.88 | SLC6A9 (0.39) | SLC6A9SLC6A5 | |
| SCHEMBL2124573 | 0.83 | SLC6A9 (0.51) | SLC6A9SLC6A5 | |
| SCHEMBL3707332 | 0.77 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL4177205 | 0.77 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL4177209 | 0.77 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL4192554 | 0.77 | SLC6A9 (0.53) | SLC6A9SLC6A5 | |
| SCHEMBL4192550 | 0.77 | SLC6A9 (0.53) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391628-A1 | 2-AZA-BICYCLOÝ2.2.1¨HEPTANE COMPOUNDS AND USES THEREOF | AstraZeneca AB (SE) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010087762-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |