Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807532 | 1.00 | JAK3 (0.54) | JAK3BTKMEN1KMT2AGAA | |
| SCHEMBL7047961 | 0.93 | JAK3 (0.51) | JAK3BTKMEN1KMT2AGAA | |
| SCHEMBL3720455 | 0.93 | JAK3 (0.51) | JAK3BTKMEN1KMT2AGAA | |
| SCHEMBL3719532 | 0.86 | JAK3 (0.47) | JAK3BTKDRD2MALT1CKS1B | |
| SCHEMBL6162860 | 0.86 | JAK3 (0.47) | JAK3BTKDRD2MALT1CKS1B | |
| SCHEMBL7344378 | 0.84 | MEN1 (0.62) | MEN1KMT2AGAADRD2MALT1 | |
| SCHEMBL6494079 | 0.79 | MEN1 (0.61) | MEN1KMT2AGAADRD2MALT1 | |
| SCHEMBL6500581 | 0.79 | MEN1 (0.61) | MEN1KMT2AGAADRD2MALT1 | |
| SCHEMBL6491658 | 0.79 | MEN1 (0.61) | MEN1KMT2AGAADRD2MALT1 | |
| SCHEMBL19345924 | 0.78 | JAK3 (0.63) | JAK3BTKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139707-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-09 | — | — | WO | disclosed |