Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583816 | 0.92 | MEN1 (0.54) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL6500581 | 0.86 | MEN1 (0.61) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL6494079 | 0.86 | MEN1 (0.61) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL6491658 | 0.86 | MEN1 (0.61) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL5807532 | 0.84 | JAK3 (0.54) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL3718682 | 0.84 | JAK3 (0.54) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL29182105 | 0.84 | MEN1 (0.49) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL10323702 | 0.84 | MEN1 (0.58) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL118384 | 0.83 | CTSK (0.51) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL266021 | 0.83 | CTSK (0.51) | MEN1KMT2AGAACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |