Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709451 | 0.84 | IKBKB (0.42) | LMNASLC6A4HTR1ASLC6A2TMEM97 | |
| SCHEMBL11073267 | 0.77 | SLC6A2 (0.49) | SLC6A4HTR1ASLC6A2HTR2AHTR2C | |
| SCHEMBL3715640 | 0.77 | DDB1 (0.53) | SLC6A4HTR1ASLC6A2PIM1PIM2 | |
| SCHEMBL28559635 | 0.76 | ACVR1B (0.50) | TMEM97SIGMAR1PIM1PIM2HRH1 | |
| SCHEMBL3714344 | 0.76 | SLC6A2 (0.44) | SLC6A4HTR1ASLC6A2TMEM97SIGMAR1 | |
| SCHEMBL18318864 | 0.75 | ACVR1B (0.47) | LMNATMEM97SIGMAR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL18319163 | 0.75 | ACVR1B (0.49) | TMEM97SIGMAR1PIM1PIM2HRH1 | |
| SCHEMBL3781660 | 0.75 | TMEM97 (0.55) | LMNASLC6A4HTR1ASLC6A2TMEM97 | |
| Hydrochloric Acid SCHEMBL18318672 | 0.74 | ACVR1B (0.46) | LMNATMEM97SIGMAR1KDM4EMAPT | |
| SCHEMBL18318482 | 0.74 | ACVR1B (0.41) | LMNATMEM97SIGMAR1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |