Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718773 | 0.84 | LMNA (0.45) | IKBKBPIM1PIM2HTR2AHTR2C | |
| SCHEMBL3715640 | 0.77 | DDB1 (0.53) | PIM1PIM2HTR2AHTR2CSLC6A4 | |
| SCHEMBL15917169 | 0.74 | NMT1 (0.46) | IKBKBCHUKSLC6A4HRH1NMT1 | |
| SCHEMBL28559635 | 0.73 | ACVR1B (0.50) | IKBKBCHUKPIM1PIM2HRH1 | |
| Hydrochloric Acid SCHEMBL18319163 | 0.73 | ACVR1B (0.49) | IKBKBCHUKPIM1PIM2HRH1 | |
| SCHEMBL18318482 | 0.72 | ACVR1B (0.41) | IKBKBCHUKPIM1PIM2LMNA | |
| SCHEMBL18318289 | 0.72 | PRKCZ (0.43) | IKBKBCHUKLMNASMN1; SMN2KDM4E | |
| SCHEMBL4539236 | 0.71 | LMNA (0.52) | LMNASMN1; SMN2KDM4ECYP3A4MAPT | |
| SCHEMBL28566761 | 0.71 | PRKCZ (0.50) | IKBKBCHUKHRH1ROCK1 | |
| SCHEMBL3784146 | 0.70 | HTR1A (0.45) | IKBKBCHUKPIM1PIM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |