Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709126 | 0.86 | CYP11B1 (0.33) | — | |
| SCHEMBL27839549 | 0.72 | CHRNB2 (0.36) | PDE1B | |
| SCHEMBL2176035 | 0.72 | — | — | |
| SCHEMBL1008998 | 0.71 | PDE1B (0.38) | PDE1B | |
| SCHEMBL13907317 | 0.69 | TACR1 (0.39) | PDE1B | |
| SCHEMBL970493 | 0.69 | PDE1B (0.32) | PDE1B | |
| SCHEMBL3714068 | 0.68 | HRH3 (0.38) | — | |
| SCHEMBL1007762 | 0.66 | PDE1B (0.35) | PDE1B | |
| SCHEMBL11551402 | 0.66 | TAAR1 (0.39) | — | |
| SCHEMBL10311190 | 0.66 | TACR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |