Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.78 |
| ▸ | TOP2A | P11388 | 2/20 | 0.78 |
| ▸ | CES2 | O00748 | 1/20 | 0.78 |
| ▸ | CES1 | P23141 | 1/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | NT5E | P21589 | 2/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | RORC | P51449 | 6/20 | 0.71 |
| ▸ | ALB | P02768 | 3/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GLI1 | P08151 | 1/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.71 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.71 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lupeol SCHEMBL7742344 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL15263404 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL21927816 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL14067725 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL148519 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL18100186 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL2734002 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL21847985 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL148518 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 | |
| Lupeol SCHEMBL17036708 | 0.88 | PTPN1 (1.00) | PTPN1TOP2ACES2CES1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134830-A1 | TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | UNIVERSIDADE DE COIMBRA (PT) | 2010-11-25 | — | — | WO | disclosed |