Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719642 | 1.00 | PRKCI (0.38) | PRKCIBUB1ADORA1ROCK2NPY2R | |
| SCHEMBL2684313 | 0.93 | PRKCI (0.37) | PRKCIBUB1ADORA1ROCK2NPY2R | |
| SCHEMBL2684309 | 0.93 | PRKCI (0.37) | PRKCIBUB1ADORA1ROCK2NPY2R | |
| SCHEMBL2685211 | 0.91 | PRKCI (0.39) | PRKCIBUB1ADORA1ROCK2NPY2R | |
| SCHEMBL2685213 | 0.91 | PRKCI (0.39) | PRKCIBUB1ADORA1ROCK2NPY2R | |
| SCHEMBL5960618 | 0.87 | ADORA1 (0.45) | ADORA1 | |
| SCHEMBL2684070 | 0.85 | GPR142 (0.40) | PRKCIALDH1A1HDAC8 | |
| SCHEMBL2684073 | 0.85 | GPR142 (0.40) | PRKCIALDH1A1HDAC8 | |
| SCHEMBL5960681 | 0.80 | ADORA1 (0.44) | ADORA1 | |
| SCHEMBL5960682 | 0.79 | ADORA1 (0.45) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |