Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.86 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.86 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152467 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3715944 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3725938 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3725941 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3719832 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3719834 | 1.00 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL12064479 | 0.89 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3891610 | 0.85 | SLC6A2 (0.85) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3662366 | 0.81 | SLC6A2 (0.56) | SLC6A2SLC6A4 | |
| SCHEMBL4240771 | 0.80 | SLC6A2 (0.77) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120889-A1 | TREATMENT OF METABOLIC SYNDROME WITH CYCLIC AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-10-21 | — | — | WO | disclosed |