Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720774 | 0.92 | GLA (0.43) | CSNK2A1GLASMN1; SMN2KDM4EINSR | |
| SCHEMBL3720743 | 0.88 | CYP1A2 (0.35) | CSNK2A1GLASMN1; SMN2KDM4EINSR | |
| SCHEMBL3718570 | 0.88 | TSHR (0.38) | CSNK2A1GLASMN1; SMN2KDM4EINSR | |
| SCHEMBL3723730 | 0.86 | SMN1; SMN2 (0.52) | CSNK2A1GLASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3717202 | 0.85 | ACACB (0.38) | MEN1LMNAKMT2AACACBCYP1A2 | |
| SCHEMBL3717279 | 0.85 | GLA (0.57) | CSNK2A1GLASMN1; SMN2ACACBTEC | |
| SCHEMBL3720790 | 0.85 | CSNK2A1 (0.41) | CSNK2A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL3720513 | 0.83 | MTNR1A (0.49) | SMN1; SMN2ACACB | |
| SCHEMBL3725388 | 0.83 | GLA (0.44) | CSNK2A1GLASMN1; SMN2LMNAACACB | |
| SCHEMBL3717016 | 0.82 | TSHR (0.37) | CSNK2A1GLASMN1; SMN2KDM4EINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |