Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372028 | 1.00 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL372262 | 1.00 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL371966 | 0.83 | RAB9A (0.55) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL371964 | 0.83 | RAB9A (0.55) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6850815 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL3906668 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4872097 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL3906662 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7117727 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL10162435 | 0.83 | PDGFRB (0.67) | PDGFRBPDGFRARAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074932-B2 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBVIE INC. | 2006-07-11 | — | — | US | claimed |
| EP-1272500-B1 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2005-05-04 | — | — | EP | claimed |
| EP-0984975-B1 | MULTICYCLIC ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-04-23 | — | — | EP | claimed |
| EP-1272500-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| JP-2002500669-A | — | — | 2002-01-08 | — | — | JP | claimed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | claimed |
| EP-0984975-A1 | MULTICYCLIC ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2000-03-15 | — | — | EP | claimed |
| US-5922683-A | ANTIBIOTICS TREATING BACTERIAL INFECTION | ABBOTT LABORATORIES (US) | 1999-07-13 | — | — | US | claimed |
| WO-1998054197-A1 | MULTICYCLIC ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1998-12-03 | — | — | WO | claimed |
| EP-2261212-B1 | Preparation of quinoline-substituted carbamate derivatives | ABBVIE INC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-2409964-B1 | Process for the preparation of carbonate derivatives | ABBOTT LAB (US) | 2016-01-27 | — | — | EP | disclosed |
| EP-1192139-B1 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2409964-A2 | Preparation of substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2261212-A2 | Preparation of quinoline-substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2001000582-A1 | PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES | ABBOTT LABORATORIES (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-0984975-A1 | MULTICYCLIC ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5922683-A | ANTIBIOTICS TREATING BACTERIAL INFECTION | ABBOTT LABORATORIES (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1998054197-A1 | MULTICYCLIC ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1998-12-03 | — | — | WO | disclosed |