Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylquinoline SCHEMBL14964865 | 1.00 | AR (0.48) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL1964102 | 0.97 | AR (0.48) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL4610834 | 0.97 | AR (0.48) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL28386605 | 0.90 | AR (0.49) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL2348982 | 0.89 | AR (0.50) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL27801875 | 0.87 | AR (0.54) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL7091019 | 0.87 | AR (0.54) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| SCHEMBL9942375 | 0.83 | DHODH (0.47) | ARNPC1RAB9AALDH1A1SMN1; SMN2 | |
| 2-Phenylquinoline SCHEMBL27910505 | 0.83 | AR (0.56) | ARNPC1RAB9ACYP3A4CYP2C9 | |
| 2-Phenylquinoline SCHEMBL28311274 | 0.79 | AR (0.59) | ARNPC1RAB9ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393819-B9 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2017-12-27 | — | — | EP | disclosed |
| EP-2393819-B1 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-2652810-A2 | RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM Opto Semiconductors GmbH (DE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080267-A2 | RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| EP-2393819-A1 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010079051-A1 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2010-07-15 | — | — | WO | disclosed |