Sugi Predict

Sugi Predict / Compounds / 2-Phenylquinoline

2-Phenylquinoline

2-Phenylquinoline

SCHEMBL7091019

CC(=O)CC(C)=O.[Ir].c1ccc(-c2ccc3ccccc3n2)cc1.c1ccc(-c2ccc3ccccc3n2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 2/20 0.54
▸ NPC1 O15118 6/20 0.51
▸ RAB9A P51151 6/20 0.51
▸ CYP3A4 P08684 2/20 0.51
▸ CYP2C9 P11712 2/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP2D6 P10635 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ ALDH1A1 P00352 6/20 0.50
▸ KDM4E B2RXH2 6/20 0.50
▸ SMN1; SMN2 Q16637 5/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ NFKB2 Q00653 1/20 0.50
▸ RELA Q04206 1/20 0.50
▸ MAPT P10636 3/20 0.49
▸ GMNN O75496 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylquinoline SCHEMBL27801875 1.00 AR (0.54) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL2348982 0.90 AR (0.50) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL27910505 0.89 AR (0.56) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL28386605 0.88 AR (0.49) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL3720362 0.87 AR (0.48) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL1964102 0.87 AR (0.48) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL14964865 0.87 AR (0.48) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL4610834 0.87 AR (0.48) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL28311274 0.85 AR (0.59) ARNPC1RAB9ACYP3A4CYP2C9
2-Phenylquinoline SCHEMBL5080767 0.85 AR (0.67) ARNPC1RAB9ACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145824-B2 Organic photoelectric functional material, method for preparing the same, use of the same, organic electronic assembly, and light-emitting device AAC MICROTECH(CHANGZHOU)CO., LTD. (CN) 2021-10-12 — — US disclosed
US-20190237678-A1 ORGANIC PHOTOELECTRIC FUNCTIONAL MATERIAL, METHOD FOR PREPARING THE SAME, USE OF THE SAME, ORGANIC ELECTRONIC ASSEMBLY, AND LIGHT-EMITTING DEVICE Nanjing Tech Universiy (CN) 2019-08-01 — — US disclosed
US-6576352-B2 Color-converting film and light-emitting apparatus using the same FUJI PHOTO FILM CO., LTD. (JP) 2003-06-10 — — US disclosed
US-20010028962-A1 Color-converting film and light-emitting apparatus using the same UDC IRELAND LIMITED (IE) 2001-10-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190237678-A1 ORGANIC PHOTOELECTRIC FUNCTIONAL MATERIAL, METHOD FOR PREPARING THE SAME, USE OF THE SAME, ORGANIC ELECTRONIC ASSEMBLY, AND LIGHT-EMITTING DEVICE FARS2, PPOX, ETFA AR 4806/4885NPC1 3420/4885RAB9A 2488/4885
US-11145824-B2 Organic photoelectric functional material, method for preparing the same, use of the same, organic electronic assembly, and light-emitting device FARS2, PPOX, ETFA AR 4806/4885NPC1 3420/4885RAB9A 2488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.