Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.47 |
| ▸ | ACACA | Q13085 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725386 | 0.92 | ACACB (0.39) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3724233 | 0.88 | ACACB (0.37) | ACACBACACACYP2C9CYP3A4PPARA | |
| SCHEMBL3726881 | 0.87 | HPGD (0.40) | ACACBACACACYP2C9CYP3A4HPGD | |
| SCHEMBL3719580 | 0.86 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL3718627 | 0.86 | ACACB (0.43) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3723787 | 0.85 | ACACB (0.44) | ACACBHPGDPPARG | |
| SCHEMBL3722838 | 0.84 | CSNK2A1 (0.40) | ACACBPPARAPPARG | |
| SCHEMBL3721927 | 0.83 | PARP10 (0.37) | ACACBACACACYP2C9CYP3A4HPGD | |
| SCHEMBL3721103 | 0.83 | PARP10 (0.37) | ACACBACACACYP2C9CYP3A4HPGD | |
| SCHEMBL3721014 | 0.83 | ACACB (0.41) | ACACBACACACYP2C9CYP3A4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |