Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TEC | P42680 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722838 | 0.92 | CSNK2A1 (0.40) | ACACBPPARGSMN1; SMN2 | |
| SCHEMBL3721614 | 0.91 | ACACB (0.36) | ACACBMAPTALDH1A1RAB9AERN1 | |
| SCHEMBL3721014 | 0.89 | ACACB (0.41) | ACACBTEC | |
| SCHEMBL3721410 | 0.87 | MAPT (0.36) | KMT2AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3723040 | 0.86 | CSNK2A1 (0.43) | ATMPPARGSMN1; SMN2 | |
| SCHEMBL3720459 | 0.86 | ACACB (0.38) | ACACBTECPDE3BPDE3A | |
| SCHEMBL3720428 | 0.85 | ACACB (0.47) | ACACBPPARGHPGD | |
| SCHEMBL3726994 | 0.85 | ACACB (0.42) | ACACBKMT2AMAPTALDH1A1ERN1 | |
| SCHEMBL3720106 | 0.85 | SMN1; SMN2 (0.49) | ACACBKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3720790 | 0.82 | CSNK2A1 (0.41) | ACACBKMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |