Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650439 | 0.86 | KDM4E (0.47) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL4046773 | 0.84 | KDM4E (0.46) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL26125291 | 0.81 | KDM4E (0.43) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28615399 | 0.81 | KMT2A (0.46) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28274610 | 0.76 | PKM (0.39) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL8638901 | 0.76 | PKM (0.39) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL27564669 | 0.76 | KDM4E (0.39) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL27896037 | 0.73 | KDM4E (0.37) | KDM4EPKMALDH1A1 | |
| SCHEMBL10872677 | 0.73 | KDM4E (0.42) | KDM4EPKMNAMPTDAOHCAR2 | |
| SCHEMBL28215532 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |
| EP-0015824-B1 | METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS | OROGIL (FR) | 1982-02-17 | — | — | EP | claimed |
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
| EP-0199675-A1 | Heterocyclic penem compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |