Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800505 | 1.00 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL372283 | 0.84 | MGAM (0.42) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL4065530 | 0.81 | CYP1A2 (0.48) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL372349 | 0.80 | CYP1A2 (0.52) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL5462379 | 0.80 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL2328850 | 0.80 | KMT2A (0.44) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL29029193 | 0.79 | PDGFRB (0.46) | CYP1A2PDGFRBPDGFRAMGAMRAB9A | |
| SCHEMBL30063057 | 0.79 | NPC1 (0.49) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28490619 | 0.79 | NPC1 (0.49) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30491145 | 0.79 | PDGFRB (0.46) | CYP1A2PDGFRBPDGFRAMGAMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272500-B1 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2005-05-04 | — | — | EP | claimed |
| CN-114957086-B | Synthesis method and application of N-trifluoromethyl sulfonyl phthalimide | 杭州师范大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114957086-A | Synthesis method and application of N-trifluoromethylsulfonyl phthalimide | 杭州师范大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-2409964-A2 | Preparation of substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2261212-A2 | Preparation of quinoline-substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2010-12-15 | — | — | EP | disclosed |