Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491381 | 0.82 | RAB9A (0.41) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL6664822 | 0.81 | CYP3A4 (0.49) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL9829481 | 0.80 | CYP1A2 (0.49) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL29800505 | 0.80 | CYP1A2 (0.44) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL372069 | 0.80 | CYP1A2 (0.44) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL29459383 | 0.77 | SMN1; SMN2 (0.41) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL28673131 | 0.77 | SMN1; SMN2 (0.41) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL2327633 | 0.77 | KMT2A (0.44) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL2327636 | 0.77 | KMT2A (0.44) | KMT2AMEN1PDGFRBPDGFRARAB9A | |
| SCHEMBL4065530 | 0.77 | CYP1A2 (0.48) | PDGFRBPDGFRARAB9ACYP1A2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099947-A1 | A NEW CLASS OF HIGHLY APOPTOTIC ANTI-CANCER AGENTS | CAGIR ALI (TR) | 2011-08-18 | — | — | WO | disclosed |