Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TEC | P42680 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721908 | 0.95 | GLA (0.41) | GLASMN1; SMN2ACACBTECPPARD | |
| SCHEMBL3718627 | 0.92 | ACACB (0.43) | GLASMN1; SMN2ACACBCYP3A4ACACA | |
| SCHEMBL3717503 | 0.88 | KCNH2 (0.36) | GLASMN1; SMN2CYP3A4 | |
| SCHEMBL3720089 | 0.86 | TEC (0.37) | ACACBACACATEC | |
| SCHEMBL3725386 | 0.86 | ACACB (0.39) | KMOACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3723730 | 0.85 | SMN1; SMN2 (0.52) | GLASMN1; SMN2ACACBCYP3A4TEC | |
| SCHEMBL3717279 | 0.85 | GLA (0.57) | GLASMN1; SMN2ACACBTECPPARD | |
| SCHEMBL3720375 | 0.83 | MCHR1 (0.35) | — | |
| SCHEMBL3726881 | 0.82 | HPGD (0.40) | KMOACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3717025 | 0.81 | PARP10 (0.40) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |