Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717503 | 0.95 | KCNH2 (0.36) | KCNH2SCN7A | |
| SCHEMBL3719459 | 0.93 | PARP10 (0.37) | PARP15PARP10 | |
| SCHEMBL3721908 | 0.89 | GLA (0.41) | MCHR1SCN7A | |
| SCHEMBL3717025 | 0.87 | PARP10 (0.40) | KCNH2SCN7APARP15PARP10 | |
| SCHEMBL3719602 | 0.87 | SCN7A (0.34) | MCHR1KCNH2SCN7APDE10APARP15 | |
| SCHEMBL3720845 | 0.84 | MTNR1A (0.46) | HRH3 | |
| SCHEMBL3720734 | 0.83 | GLA (0.43) | — | |
| SCHEMBL3726083 | 0.83 | GLA (0.39) | — | |
| SCHEMBL3722669 | 0.83 | PARP10 (0.37) | MCHR1PARP15PARP10 | |
| SCHEMBL3721858 | 0.82 | GLA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |