SCHEMBL3720907

SCHEMBL3720907

COc1ncc(-c2ccncc2)cc1NC(=O)[C@H](Cc1ccccc1)NCCc1ccccn1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR142 Q7Z601 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2685598 0.82 GPR142 (0.57) GPR142
SCHEMBL2684297 0.82 GPR142 (0.69) GPR142
SCHEMBL2684301 0.82 GPR142 (0.69) GPR142
SCHEMBL2684659 0.82 GPR142 (0.60) GPR142
SCHEMBL2684662 0.82 GPR142 (0.60) GPR142
SCHEMBL2686180 0.81 GPR142 (0.65) GPR142
SCHEMBL2686173 0.81 GPR142 (0.65) GPR142
SCHEMBL2683134 0.81 GPR142 (0.60) GPR142
SCHEMBL3716298 0.80 GPR142 (0.69) GPR142
SCHEMBL2684873 0.80 GPR142 (1.00) GPR142

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010093849-A2 PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS AMGEN INC. (US) 2010-08-19 WO disclosed