Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.33 |
| ▸ | ACACA | Q13085 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724495 | 0.91 | PDE3B (0.34) | ACACBACACAMAPK1FFAR4PPARG | |
| SCHEMBL3716838 | 0.89 | ACACB (0.33) | ACACBACACAMAPTCYP1A2CYP2C9 | |
| SCHEMBL3720790 | 0.88 | CSNK2A1 (0.41) | ACACBMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL3726328 | 0.86 | ACACB (0.40) | ACACBACACACYP1A2MAPK1 | |
| SCHEMBL3717723 | 0.85 | TLR8 (0.33) | ACACBACACAMAPTCYP1A2CYP2C9 | |
| SCHEMBL3720743 | 0.85 | CYP1A2 (0.35) | MAPTCYP1A2MAPK1MEN1GAA | |
| SCHEMBL3719226 | 0.84 | GPBAR1 (0.35) | ACACBP2RX3PPARG | |
| SCHEMBL3724297 | 0.83 | ACACB (0.38) | ACACBMAPTMAPK1PPARGTLR8 | |
| SCHEMBL3720703 | 0.82 | PDE4B (0.36) | PDE4BSCN9APPARG | |
| SCHEMBL3720075 | 0.82 | SCN9A (0.35) | PDE4BSCN9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |