Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.40 |
| ▸ | ACACA | Q13085 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725360 | 0.88 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3724495 | 0.86 | PDE3B (0.34) | ACACBACACAMAPK1POLBPDE3B | |
| SCHEMBL3716838 | 0.86 | ACACB (0.33) | ACACBACACAMAPK1CYP1A2 | |
| SCHEMBL3721090 | 0.86 | ACACB (0.33) | ACACBACACAMAPK1CYP1A2 | |
| SCHEMBL3719990 | 0.85 | LMNA (0.37) | ACACB | |
| SCHEMBL3717771 | 0.85 | MEN1 (0.37) | ACACBACACAMAPK1PDE3BPDE3A | |
| SCHEMBL3719552 | 0.85 | PDE3B (0.34) | ACACBACACAMAPK1POLBPDE3B | |
| SCHEMBL3720459 | 0.85 | ACACB (0.38) | ACACBACACAPDE3BPDE3ACYP3A4 | |
| SCHEMBL3720790 | 0.85 | CSNK2A1 (0.41) | ACACB | |
| SCHEMBL3717201 | 0.85 | ACACB (0.38) | ACACBACACAMAPK1POLBPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |