Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.47 |
| ▸ | ACACA | Q13085 | 9/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717123 | 0.89 | ACACB (0.50) | ACACBACACA | |
| SCHEMBL3722765 | 0.87 | ACACB (0.45) | ACACBACACASCN9A | |
| SCHEMBL3719630 | 0.84 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL3727673 | 0.84 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3727054 | 0.84 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL3726200 | 0.83 | ACACB (0.57) | ACACBACACA | |
| SCHEMBL3720168 | 0.83 | HTT (0.49) | ACACBACACA | |
| SCHEMBL3727572 | 0.83 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3724135 | 0.82 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL13076463 | 0.82 | ACACB (0.46) | ACACBACACASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |