Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437616 | 0.78 | PTPN1 (0.47) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL10995517 | 0.78 | PTPN1 (0.46) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL10995738 | 0.77 | PTPN1 (0.49) | PTPN1ACP1CDC25B | |
| SCHEMBL1670284 | 0.77 | PTPN1 (0.46) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL10996134 | 0.75 | HSD11B1 (0.36) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL70825 | 0.73 | PTPN1 (0.56) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL13403500 | 0.71 | PTPN1 (0.59) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL8194669 | 0.71 | PTPN1 (0.59) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 | |
| SCHEMBL9730908 | 0.71 | — | — | |
| SCHEMBL5146314 | 0.70 | PTPN1 (0.57) | PTPN1ACP1CDC25BALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472267-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | Sixfold Bioscience Ltd. (GB) | 2025-11-18 | — | — | US | claimed |
| CN-115997016-A | Composition comprising nucleic acid nanoparticles having modular functional groups | 西克斯福德生物科学有限公司 | 2023-04-21 | — | — | CN | claimed |
| EP-4143316-A2 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | Sixfold Bioscience Ltd. (GB) | 2023-03-08 | — | — | EP | claimed |
| US-20220370635-A1 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | SIXFOLD BIOSCIENCE LTD (GB) | 2022-11-24 | — | — | US | claimed |
| US-11357865-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | Sixfold Bioscience Ltd. (GB) | 2022-06-14 | — | — | US | claimed |
| WO-2021220053-A2 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | Sixfold Bioscience Ltd. (GB) | 2021-11-04 | — | — | WO | claimed |
| US-20210330810-A1 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | Sixfold Bioscience Ltd. (GB) | 2021-10-28 | — | — | US | claimed |
| US-4547516-A | Antisecretory agents derived from meldrum's acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-10-15 | — | — | US | claimed |
| US-20260049991-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS | GLYPHIC BIOTECHNOLOGIES INC (US) | 2026-02-19 | — | — | US | disclosed |
| EP-4655289-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS | Glyphic Biotechnologies, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| US-12472267-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | Sixfold Bioscience Ltd. (GB) | 2025-11-18 | — | — | US | disclosed |
| US-20250289830-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY | 2025-09-18 | — | — | US | disclosed |
| EP-4594520-A2 | COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS | Sixfold Bioscience Ltd. (GB) | 2025-08-06 | — | — | EP | disclosed |
| US-12351591-B2 | KRas inhibitors | ELI LILLY AND COMPANY (US) | 2025-07-08 | — | — | US | disclosed |
| US-5179216-A | Anticholesterol agents and atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-5177219-A | N-phenyl-N'-thienylmethyl-bis-diamino-5-methylene-1,3-dioxane-4,6-dione compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| US-5164505-A | Anticholesterol, inhibitors of acyl-coenzyme A:cholesterol-acyl transferase (ACAT) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| US-5136039-A | N,N',N'-trisubstituted-5-bis-aminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-CoA:cholesterol-acyl transferase | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0471493-A1 | N,N',N'-trisubstituted-5-bisaminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-CoA:cholesterol-acyl transferase | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-19 | — | — | EP | disclosed |
| US-4547516-A | Antisecretory agents derived from meldrum's acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357865-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | NCL, NSUN3, POLN | PTPN1 2682/4885ACP1 361/4885CDC25B 3875/4885 |
| US-20260049991-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS | CHAMP1, S100A11, TFIP11 | PTPN1 2383/4885ACP1 16/4885CDC25B 3887/4885 |
| US-20220370635-A1 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | NCL, NSUN3, POLN | PTPN1 2682/4885ACP1 361/4885CDC25B 3875/4885 |
| US-20210330810-A1 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | NCL, NSUN3, POLN | PTPN1 2682/4885ACP1 361/4885CDC25B 3875/4885 |
| US-12351591-B2 | KRas inhibitors | KRAS, NRAS, HRAS | PTPN1 547/4885ACP1 3885/4885CDC25B 291/4885 |
| US-12472267-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | NCL, NSUN3, POLN | PTPN1 2682/4885ACP1 361/4885CDC25B 3875/4885 |
| US-20250289830-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | PTPN1 547/4885ACP1 3885/4885CDC25B 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.