Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 15/20 | 0.51 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721668 | 0.91 | PRLHR (0.41) | PRLHRPDE10A | |
| SCHEMBL3717902 | 0.85 | PRLHR (0.50) | PRLHRPDE10A | |
| SCHEMBL3717977 | 0.83 | PRLHR (0.44) | PRLHR | |
| SCHEMBL3716358 | 0.82 | PRLHR (0.54) | PRLHR | |
| SCHEMBL3716853 | 0.81 | PRLHR (0.49) | PRLHR | |
| SCHEMBL3714275 | 0.81 | PRLHR (0.48) | PRLHR | |
| SCHEMBL3713142 | 0.81 | PRLHR (0.42) | PRLHR | |
| SCHEMBL3714329 | 0.81 | PRLHR (0.55) | PRLHR | |
| SCHEMBL3721671 | 0.80 | PRLHR (0.51) | PRLHRMTOR | |
| SCHEMBL434516 | 0.79 | PRLHR (0.70) | PRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |