SCHEMBL3721671

SCHEMBL3721671

CC(C)(C)OC(=O)N1CCc2nc(NCCc3ccc(C(F)(F)F)cc3)n(N3CCOCC3)c(=O)c2C1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 19/20 0.51
MTOR P42345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716816 0.84 PRLHR (0.52) PRLHR
SCHEMBL434516 0.84 PRLHR (0.70) PRLHR
SCHEMBL3717980 0.83 PRLHR (0.52) PRLHR
SCHEMBL3712993 0.82 PRLHR (0.54) PRLHR
SCHEMBL3716854 0.82 PRLHR (0.55) PRLHR
SCHEMBL3714279 0.82 PRLHR (0.52) PRLHR
SCHEMBL3713144 0.82 PRLHR (0.51) PRLHR
SCHEMBL3714330 0.81 PRLHR (0.55) PRLHR
SCHEMBL3719911 0.81 PRLHR (0.60) PRLHR
SCHEMBL3721670 0.80 PRLHR (0.51) PRLHRMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed