Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121132 | 1.00 | RXFP1 (0.43) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL2119575 | 0.93 | KMT2A (0.38) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL479549 | 0.93 | KMT2A (0.38) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL2573629 | 0.89 | RXFP1 (0.49) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL480669 | 0.88 | RXFP1 (0.47) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL480592 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL479845 | 0.86 | RXFP1 (0.47) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL2119035 | 0.86 | RXFP1 (0.47) | RXFP1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL4497417 | 0.86 | RXFP1 (0.35) | RXFP1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3714840 | 0.86 | SMN1; SMN2 (0.47) | RXFP1SMN1; SMN2RAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |