Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123046 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL2123050 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL2573629 | 0.93 | RXFP1 (0.49) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL3713856 | 0.91 | RAB9A (0.44) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL2122346 | 0.91 | RAB9A (0.44) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL2122343 | 0.91 | RAB9A (0.44) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL481166 | 0.91 | RXFP1 (0.51) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL481167 | 0.91 | RXFP1 (0.51) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL479804 | 0.90 | BACE1 (0.51) | SMN1; SMN2NPC1RAB9AGAARXFP1 | |
| SCHEMBL479808 | 0.90 | BACE1 (0.51) | SMN1; SMN2NPC1RAB9AGAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |