SCHEMBL3721982

SCHEMBL3721982

CC1=C(C)C([Hf])(C2C=Cc3ccccc32)C(C)=C1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4848230 0.98 HTR6 (0.31) HTR6HTR2A
SCHEMBL6378838 0.79 HTR6 (0.32) HTR6HTR2ASIGMAR1
Hydrochloric Acid SCHEMBL8623411 0.78 BRD4 (0.32) HTR6HTR2A
Hydrochloric Acid SCHEMBL4852332 0.78 HTR6 (0.31) HTR6HTR2A
SCHEMBL7176934 0.78
SCHEMBL2784485 0.74
SCHEMBL7046153 0.74
Hydrochloric Acid SCHEMBL2785614 0.73
Hydrochloric Acid SCHEMBL6469236 0.73
SCHEMBL6310863 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392743-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM Univation Technologies LLC (US) 2004-03-03 EP claimed
US-20040039138-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2004-02-26 US claimed
US-6620894-B2 Calibration; using coordination catalyst UNIVATION TECHNOLOGIES, LLC 2003-09-16 US claimed
US-20020132937-A1 Start-up procedure for multiple catalyst polymerization systems UNIVATION TECHNOLOGIES, LLC 2002-09-19 US claimed
WO-2002046250-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2002-06-13 WO claimed
CN-118339199-A Gas phase process for preparing polypropylene random copolymer 格雷斯公司 2024-07-12 CN disclosed
CN-118055955-A Process for producing polyolefin granular resins with increased settled bulk density 格雷斯公司 2024-05-17 CN disclosed
WO-2023178116-A1 SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM W. R. GRACE & CO.-CONN (US) 2023-09-21 WO disclosed
EP-4223802-A2 POLYMERIZATION CATALYST Univation Technologies, LLC (US) 2023-08-09 EP disclosed
EP-2953985-B1 PREPARATION OF POLYOLEFIN UNIVATION TECH LLC (US) 2023-06-07 EP disclosed
EP-3998293-A1 PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY Univation Technologies, LLC (US) 2022-05-18 EP disclosed
EP-3998292-A1 PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY Univation Technologies, LLC (US) 2022-05-18 EP disclosed
EP-0811637-A2 Method for feeding a liquid catalyst to a fluidized bed polmerization reactor UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-12-10 EP disclosed
US-5693727-A INTRODUCING MONOMERS INTO POLYMERIZATION ZONE CONTAINING BED OF GROWING POLYMER PARTICLES, INTRODUCING UNSUPPORTED POLYMERIZATION CATALYST IN LIQUID FORM INTO VESSEL, WITHDRAWING POLYMERIC PRODUCT, UNREACTED MONOMERS, GASES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-12-02 US disclosed
CN-1165151-A Process for production of long-chain branched polyolefins UNION CARBIDE CHEM PLASTIC (US) 1997-11-19 CN disclosed
EP-0784062-A2 Process for production of long-chain branched polyolefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-07-16 EP disclosed
EP-0770629-A2 A process for preparing an in situ polyethylene blend UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-05-02 EP disclosed
EP-0593083-B1 Gas phase polymerization reaction utilizing soluble unsupported catalysts UNION CARBIDE CHEM PLASTIC (US) 1996-05-01 EP disclosed
US-5317036-A Continuous catalytic vapor phase polymerization of olefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-05-31 US disclosed
EP-0593083-A1 Gas phase polymerization reaction utilizing soluble unsupported catalysts UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-20 EP disclosed