Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | UTRN | P46939 | 9/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052930 | 0.88 | ESR1 (0.57) | TP53SMN1; SMN2UTRNHDAC6CYP1A2 | |
| SCHEMBL19846155 | 0.86 | KDM4E (0.57) | TP53SMN1; SMN2ESR1ESR2MAPT | |
| SCHEMBL25498923 | 0.84 | SMN1; SMN2 (0.62) | TP53SMN1; SMN2HDAC6CYP1A2ESR1 | |
| SCHEMBL29407356 | 0.84 | SMN1; SMN2 (0.66) | TP53SMN1; SMN2HDAC6CYP1A2ESR1 | |
| SCHEMBL9966868 | 0.84 | SMN1; SMN2 (0.66) | TP53SMN1; SMN2HDAC6CYP1A2ESR1 | |
| SCHEMBL10173054 | 0.84 | HDAC6 (0.64) | TP53SMN1; SMN2HDAC6ESR1ESR2 | |
| SCHEMBL15844590 | 0.83 | UTRN (0.56) | TP53SMN1; SMN2UTRNHDAC6CYP1A2 | |
| SCHEMBL2243139 | 0.82 | RAB9A (0.72) | TP53SMN1; SMN2ESR1ESR2MAPT | |
| SCHEMBL30727501 | 0.82 | NPC1 (0.62) | TP53SMN1; SMN2UTRNHDAC6CYP1A2 | |
| SCHEMBL1913541 | 0.82 | NPC1 (0.62) | TP53SMN1; SMN2UTRNHDAC6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112093-A1 | BENZOXAZOLES FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-10-07 | — | — | WO | disclosed |