Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728850 | 0.87 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL3725816 | 0.87 | MTOR (0.56) | MTORPIK3CA | |
| SCHEMBL3725499 | 0.86 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL3723157 | 0.82 | MTOR (0.55) | MTORPIK3CA | |
| SCHEMBL2097833 | 0.81 | MTOR (0.78) | MTORPIK3CA | |
| SCHEMBL3723269 | 0.81 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL3723092 | 0.79 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL3717802 | 0.79 | MTOR (0.56) | MTORPIK3CA | |
| SCHEMBL3723022 | 0.78 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL3718606 | 0.77 | MTOR (0.60) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120996-A1 | 5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH LLC (US) | 2010-10-21 | — | — | WO | claimed |
| WO-2010120996-A1 | 5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH LLC (US) | 2010-10-21 | — | — | WO | disclosed |