Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL23849548 | 0.87 | LMNA (0.46) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL77705 | 0.87 | LMNA (0.50) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL8206022 | 0.87 | LMNA (0.50) | LMNAMMP1MMP2MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL1036864 | 0.85 | LMNA (0.48) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL8211316 | 0.85 | LMNA (0.48) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL7443873 | 0.81 | LMNA (0.44) | LMNAMMP1MMP2MMP3MMP8 | |
| Aminomethylamide SCHEMBL8819200 | 0.80 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| Glycine SCHEMBL18490910 | 0.80 | GLRA1 (0.40) | LMNAALDH1A1TDP1HPGDGLA | |
| Alanine SCHEMBL18490944 | 0.80 | LMNA (0.40) | LMNAALDH1A1TDP1HPGDGLA | |
| Phosphonic Acid SCHEMBL5490946 | 0.79 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009897-A1 | COMPOSITIONS AND METHODS FOR PRESERVING RED BLOOD CELLS AND PLATELETS | RYTHRX THERAPEUTICS, LLC (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20100093609-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TSRL, INC. | 2010-04-15 | — | — | US | disclosed |
| WO-2008121941-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TSRL, INC. (US) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093609-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TYMP, SLC1A5, TYMS | LMNA 3539/4885MMP1 821/4885MMP2 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.