Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.72 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466284 | 0.95 | PTGDR2 (0.77) | PTGDR2PTGIRPTGDR | |
| SCHEMBL3717896 | 0.92 | PTGDR2 (0.60) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1466930 | 0.88 | PTGDR2 (0.73) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1466741 | 0.88 | PTGDR2 (0.66) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1598755 | 0.84 | PTGDR2 (1.00) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1466910 | 0.84 | PTGDR2 (1.00) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1465961 | 0.82 | PTGDR2 (0.75) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1467394 | 0.81 | PTGDR2 (0.85) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1466927 | 0.81 | PTGDR2 (0.75) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1921057 | 0.81 | PTGDR2 (0.56) | PTGDR2PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |